Dna polymerase κ suppresses inflammation and inflammation-induced mutagenesis and carcinogenic potential in the colon of mice

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  • who: Atsushi Hakura from the Ibaraki, u20112635, Japan University, Otsu, Shiga, u20110811, Japan have published the article: DNA polymerase u03ba suppresses inflammation and inflammation-induced mutagenesis and carcinogenic potential in the colon of mice, in the Journal: (JOURNAL)
  • what: The authors examined whether Pol suppressed inflammationinduced colon tumorigenesis by treating inactivated Polk knock-in (Polk-/-) mice with dextran sulfate sodium (DSS) an inducer of colon Results Male and female Polk-/- and Polk+/+ mice were administered 2% DSS in drinking water for six consecutive days succeeded via a recovery period of 16 days followed by 2 . . .

     

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