Dna sequence-dependent formation of heterochromatin nanodomains

HIGHLIGHTS

  • who: Graeme J. Thorn from the SchoolUniversity of London, Gower St, Bloomsbury, London WC E BT, UK have published the article: DNA sequence-dependent formation of heterochromatin nanodomains, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors investigate the mechanism by which four different types of HNDs form. Partial unwrapping of DNA from the nucleosome core at single-nucleotide resolution as well as competitive and cooperative DNA binding of different protein species was implemented according to the approach described previously38,39. Another important feature of the model is the contribution of nucleosome-binding proteins . . .

     

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