Dnase c is the effector endonuclease for internucleosomal dna fragmentation in necrosis

HIGHLIGHTS

• who: Ryushin Mizuta and colleagues from the Research Institute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, Japan, Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo have published the research: DNase c Is the Effector Endonuclease for Internucleosomal DNA Fragmentation in Necrosis, in the Journal: PLOS ONE | www.plosone.org of July/19,/2013
• what: The authors show that (i) INDF occurs even during necrosis in cell lines primary cells and in tissues of mice in vivo and_(ii) DNase c but not CAD is the effector endonuclease for INDF in cells undergoing necrosis . . .
  

   

  

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