HIGHLIGHTS
- who: Xuan Chu from the Central Laboratory of Yong-Chuan Hospital, Chongqing Medical University, Chongqing, China have published the paper: DNMT3A R882H mutation drives daunorubicin resistance in acute myeloid leukemia via regulating NRF2/NQO1 pathway, in the Journal: (JOURNAL)
- what: The authors found that AML cells with DNMT3A R882H had higher Bcl2, Bcl-xl and Mcl1 expressions compared with those in WT_cells. K, L Immunoblot of NRF2 and NQO1 expressions in DNMT3A WT and mutant KG-1a cells and THP1 cells after treated with 0.4 u03bcM DNR and harvested at different times Certainly, the . . .
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