Docetaxel-loaded m1 macrophage-derived exosomes for a safe and efficient chemoimmunotherapy of breast cancer

HIGHLIGHTS

  • who: Yongmei Zhao from the School of Pharmacy, Nantong University, Nantong, China NICM Health Research Institute, Western Sydney University, Westmead, NSW, Australia , have published the paper: Docetaxel-loaded M1 macrophage-derived exosomes for a safe and efficient chemoimmunotherapy of breast cancer, in the Journal: (JOURNAL)
  • what: For the first time, the authors report chemotherapy-enabled macrophage programming strategy via modulating mitochondrial functions, aiming to achieve highly effective immunotherapy.
  • how: Data were analyzed using the IncuCyte software. The results showed that DTX-M1-Exo prolonged M1 macrophage polarization even upon M2 macrophage stimulation. In . . .

     

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