HIGHLIGHTS
- who: Yangping Wu et al. from the University of Santiago de Compostela, Spain have published the research: DOG1 as a novel antibody-drug conjugate target for the treatment of multiple gastrointestinal tumors and liver metastasis, in the Journal: (JOURNAL)
- what: Increased expression of DOG1 among various neoplasms of alimentary tract and metastasis First, the authors evaluate the importance of DOG1 in human cancers from the digestive system, including esophagus, stomach, liver and colon. The authors aim to generate ADCs with anti-DOG1 to improve the therapeutic efficacy. The study demonstrates that the anti-DOG1-DM4 . . .
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