Domain and functional analysis of a novel breast tumor suppressor protein, scube2*

HIGHLIGHTS

  • who: Yuh-Charn Lin from the (UNIVERSITY) have published the research work: Domain and Functional Analysis of a Novel Breast Tumor Suppressor Protein, SCUBE2*, in the Journal: (JOURNAL) of July/29,/2011
  • what: The authors investigated whether the NH2-terminal EGF-like repeats or the COOH-terminal CUB domain of SCUBE2 could independently execute the growth suppression function of SCUBE2 in MCF-7 breast cancer cells. The NH2-terminal EGF-like Repeat Motif of SCUBE2 Acts as a Homophilic Adhesive Module in a Calcium-dependent Fashion-To further elucidate the function and signaling mediated by . . .

     

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