Donor myeloid derived suppressor cells (mdscs) prolong allogeneic cardiac graft survival through programming of recipient myeloid cells in vivo

HIGHLIGHTS

• who: Songjie Cai from the s Hospital have published the research: Donor myeloid derived suppressor cells (MDSCs) prolong allogeneic cardiac graft survival through programming of recipient myeloid cells in vivo, in the Journal: Scientific Reports Scientific Reports of 23/Dec/2019
• how: The data were analyzed using GraphPad Prism version 5.0 (GraphPad Software).

SUMMARY

Donor‑derived MDSCs suppress alloreactive T_cell activation in_vitro. Co-culturing naive T_cells isolated from C57BL/6 mice ­(H2Kb, I-Ab) with BALB/c ­(H2Kd, I-Ad) derived conventional DCs (cDCs) stimulates an alloreactive T_cell proliferation. The . . .

 



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