Dopamine transporter, phosphoserine129 -synuclein and -synuclein levels in aged lrrk2 g2019s knock-in and knock-out mice

HIGHLIGHTS

• who: Chiara Domenicale and colleagues from the Department Neuroscience and Rehabilitation, University, Italy have published the Article: Dopamine Transporter, PhosphoSerine129 -Synuclein and -Synuclein Levels in Aged LRRK2 G2019S Knock-In and Knock-Out Mice, in the Journal: Biomedicines 2022, 881 of /2022/
• what: In confirming aberrant DAT and VMAT2 levels and dysfunctional DAT in 12-month-old G2019S KI mice, the authors show for the first time that DAT changes preceded and outlasted VMAT2 changes, and that DAT dysfunction is not sustained by ongoing LRRK2 kinase activity.
• how: Statistical analysis was implemented in . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.