Dose-dependent biphasic action of quetiapine on ampk signalling via 5-ht7 receptor: exploring pathophysiology of clinical and adverse effects of quetiapine

HIGHLIGHTS

  • who: Motohiro Okada and collaborators from the Department of Neuropsychiatry, Division of Neuroscience, Graduate School of Medicine, Mie University, Tsu, Japan have published the Article: Dose-Dependent Biphasic Action of Quetiapine on AMPK Signalling via 5-HT7 Receptor: Exploring Pathophysiology of Clinical and Adverse Effects of Quetiapine, in the Journal: (JOURNAL) of 19/07/2022
  • what: To explore the mechanisms underlying the clinical and adverse reactions to atypical antipsychotics this study determined the effects of the sub-chronic administration of quetiapine (QTP: 3~30 µM) on the protein expression of_(5-HT7R) connexin43 (Cx43) cAMP . . .

     

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