Dose-dependent consequences of sub-chronic fentanyl exposure on neuron and glial co-cultures

HIGHLIGHTS

• who: . and colleagues from the Germany Germany Germany have published the article: Dose-dependent consequences of sub-chronic fentanyl exposure on neuron and glial co-cultures, in the Journal: (JOURNAL)
• what: The authors determine that only the cultures treated with the low dose of fentanyl displayed a significant (1.15-fold) increase in LDH levels, relative to the untreated controls. The authors next examined genes belonging to selected biological processes, in particular the authors focused on upregulated genes associated with inflammatory responses, extracellular matrix and synaptic transmission .
• future: Future work is needed to . . .
  

   

  

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