Double-stranded dna induces a prothrombotic phenotype in the vascular endothelium

HIGHLIGHTS

  • who: Erik Gaitzsch from the (UNIVERSITY) have published the research: Double-stranded DNA induces a prothrombotic phenotype in the vascular endothelium, in the Journal: Scientific Reports Scientific Reports of 23/01/2017
  • what: The aim of this study was to characterize prothrombotic effects of dsDNA in vascular endothelial cells. The authors show that viral or endogenous dsDNA a prothrombotic phenotype in the vascular endothelium. The authors show direct prothrombotic effects of intracellular double stranded DNA (dsDNA) in the vascular endothelium. dsDNA led to upregulation of the procoagulatory proteins tissue factor and PAI-1 and increased . . .

     

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