HIGHLIGHTS
- who: Gang Xi from the The abbreviations used are: IGF, insulin-like growth factor have published the research: Down-regulation of Insulin Receptor Substrate 1 during Hyperglycemia Induces Vascular Smooth Muscle Cell Dedifferentiation*, in the Journal: (JOURNAL) of September/15,/2016
- how: The results showed that wounding treatment induced PCNA in diabetic wild-type and non-diabetic IRS-1⫺/⫺ mice whereas SM22 and ␣-actin expression were remarkably reduced (Fig 7C).
SUMMARY
Despite intense analysis, the molecular mechanism by which glucose lowering results in a clinical benefit has remained poorly defined. The . . .
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