HIGHLIGHTS
- who: Down Syndrome Fetal Fibroblasts et al. from the University of Catania, Italy have published the paper: Down Syndrome Fetal Fibroblasts Display Alterations of Endosomal Traf fi cking Possibly due to SYNJ1 Overexpression, in the Journal: (JOURNAL)
- what: In DS Here, the authors show that the structure and dynamics of EEs, but not of late endosomes, are strikingly altered in DS cells.
- future: Studies are necessary to elucidate these aspects.
SUMMARY
Other members of this class of enzymes, Synj1 harbors two consecutive phosphatase domains, Sac1 and 5phosphatase, which dephosphorylates . . .
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