HIGHLIGHTS
- who: Hyunkoo Kang from the Department of Integrated Biological Science, Pusan National University, Busan, Republic of have published the article: Downregulated CLIP3 induces radioresistance by enhancing stemness and glycolytic flux in glioblastoma, in the Journal: (JOURNAL)
- what: The authors report that GSCs that survive standard treatment radiation upregulate Speedy/RINGO cell cycle regulator family member A (Spy1) and downregulate CAP-Gly domain containing linker protein 3 (CLIP3 also known as CLIPR-59). Because the expression of CLIP3, but not Spy1, constantly changed after IR, the authors focused on CLIP3 activating drugs that might have a . . .
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