Downregulation of elovl5 promotes breast cancer metastasis through a lipid-droplet accumulation-mediated induction of tgf-β receptors

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  • who: Trinh-Le-Vi Kieu from the Mice were bred and maintained in the animal facility of the University of Burgundy according to the center instructions, all the experiments were carried out following the instructions of the Federation of European Animal Science AssociationsExperimental designs involving animals were approved by the Ethics Committee of the University of Burgundy (projects #17461, #, and #22358). Elovl5-/- C BL/ N mice were obtained from the Mutant Mouse Regional Resource Center at UC Davis (Davis, CA) and were generated by inserting a genetrap cassette in the exon , of the Elovl, gene., .FVB-Tg . . .

     

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