Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating the tgf-β/collagen pathway in preeclampsia

HIGHLIGHTS

• who: Xiang-Hong Xu from the of the subjects are summarized in Table S The preeclampsia group was defined as onset of hypertension , weeks after gestation with a systolic blood pressure of , mmHg and/or diastolic blood pressure of , mmHg at least two separate measurements (at least , h, but with a ≤7-day interval) and consistent proteinuria (, mg in a, h urine collection period or, + protein by dipstick detection) according to the guidelines of the US National Institutes of Health24. Small pieces (approximately, ., cm3) were cut from the fetal part of the placenta under aseptic conditions and . . .
  

   

  

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