Downregulation of mir-205 and mir-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells

HIGHLIGHTS

• who: N Bhatnagar from the DepartmentState University of Medicine, Tuxedo, NY, USA have published the research work: Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells, in the Journal: (JOURNAL)
• what: As these cell lines all express low levels of miR-205 and miR-31, the authors reason that other drug-resistance mechanisms may contribute to the observed differences among their responses to these agents. The authors have demonstrated that miR-205 and miR-31 regulate apoptosis in prostate cancer cells by targeting antiapoptotic proteins Bcl-w . . .
  

   

  

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