Downregulation of s100a9 reverses cisplatin-resistance and inhibits proliferation and migration in hypopharyngeal carcinoma

HIGHLIGHTS

  • who: Carcinoma and collaborators from the Department of Otolaryngology-Head Neck Surgery, The Third Xiangya Hospital of Central South University, Changsha, Hunan Province, China have published the research: Downregulation of S100A9 Reverses Cisplatin-Resistance and Inhibits Proliferation and Migration in Hypopharyngeal Carcinoma, in the Journal: Journal of Oncology
  • what: The study demonstrated that downregulation of S100A9 remarkably inhibited the migration and proliferation and reversed resistance of HPC to cisplatin.
  • how: To screen the differential expression genes (DEGs) and proteins (DEPs) the authors conducted transcriptomic and proteomic analysis on cisplatin-sensitive cell lines (FaDu . . .

     

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