Downregulation of tcf1 in hiv infection impairs t-cell proliferative capacity by disrupting mitochondrial function

HIGHLIGHTS

• who: Hong Shang and Zi-Ning Zhang from the NHC Key Laboratory of AIDS Immunology, National Clinical Research Center for Laboratory Medicine, The First Affiliated of China Medical University, Shenyang, China, Department of Central Laboratory, Municipal Central have published the Article: Downregulation of TCF1 in HIV Infection Impairs T-cell Proliferative Capacity by Disrupting Mitochondrial Function, in the Journal: (JOURNAL)
• what: The authors firstly observed downregulation of TCF1 in individuals with HIV compared with NC and ART individuals, in both CD8+ and CD4+ T-cells, and confirmed a positive correlation between TCF1 downregulation and disease . . .
  

   

  

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