Downregulation of the rho gtpase pathway abrogates resistance to ionizing radiation in wild-type p53 glioblastoma by suppressing dna repair mechanisms

HIGHLIGHTS

  • who: Yuli Thamires Magalhaes from the (UNIVERSITY) have published the article: Downregulation of the Rho GTPase pathway abrogates resistance to ionizing radiation in wild-type p53 glioblastoma by suppressing DNA repair mechanisms, in the Journal: (JOURNAL) of 13/04/2023
  • what: The authors investigated the contributions of the Rho pathway and actin cytoskeleton dynamics in the acquisition of ionizing_radiation (IR) resistance in GBM and their potential interdependence with the p53 status in terms of its association with DNA damage response and repair pathways.
  • how: DNA was stained with SYBR Green II (Invitrogen) and . . .

     

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