Doxorubicin-induced platelet activation and clearance relieved by salvianolic acid compound: novel mechanism and potential therapy for chemotherapy-associated thrombosis and thrombocytopenia

HIGHLIGHTS

  • who: Wenjing Ma and collaborators from the Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M S , Canada have published the research: Doxorubicin-Induced Platelet Activation and Clearance Relieved by Salvianolic Acid Compound: Novel Mechanism and Potential Therapy for Chemotherapy-Associated Thrombosis and Thrombocytopenia, in the Journal: Pharmaceuticals 2022, 15, x FOR PEER REVIEW of /2022/
  • what: The authors investigated the direct influence of Dox on platelets including activation, clearance, and intracellular signalling pathways, as well as the ability of SAC to attenuate these effects. With these considerations, the authors focused on . . .

     

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