HIGHLIGHTS
- who: Mohammed A. A. Saleh from the Division of Systems Pharmacology and Pharmacy, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands have published the article: Drug Distribution in Brain and Cerebrospinal Fluids in Relation to IC, in the Journal: (JOURNAL)
- what: This study provides insights into the relations between CNS compartments PK profiles including target sites. u00adCSFSAS PK appears to be an unreliable predictor of brain PK. Despite extensive changes in blood-brain barrier and brain properties in Alzheimer`s this study shows that the impact of aging and Alzheimer`s pathology . . .
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