HIGHLIGHTS
- who: Eun Ae Ko from the Yonsei University have published the paper: Drug repositioning of polaprezinc for bone fracture healing, in the Journal: (JOURNAL) of 14/04/2021
- what: Previous studies have demonstrated that zinc acts a signaling molecule in various intracellular signaling pathways10 11 and the research has indicated that zinc is involved in the calcium-calcineurin-NFATc1 signaling pathway to inhibit osteoclast differentiation in mouse bone marrow-derived monocytes (mBMMs) as well as the AMPPKA-CREB signaling pathway to promote osteoblast differentiation in human bone marrow-derived mesenchymal stem cells (hBMSCs)12 13 . . .
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