Drug repositioning via host-pathogen protein-protein interactions for the treatment of cervical cancer

HIGHLIGHTS

SUMMARY

    Methods: Accordingly, in this study, the authors emphasize the potential of host proteins as drug_targets and identify promising host protein candidates for cervical cancer by considering potential differences between HPV subtypes (i.e., HPV16 and HPV18) within a novel bioinformatics framework that the authors have developed. Keyword host-oriented drugs, host-pathogen protein-protein interactions, cervical cancer, HPV, drug repurposing Frontiers in Oncology frontiersin.org 10.3389/fonc.2023.1096081 For this reason, the authors set a prerequisite and four parameters separately to reveal their potential as drug_targets. By integrating these four parameters, the . . .

     

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