Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy

HIGHLIGHTS

• Who: Vipin Rawat and colleagues from the DepartmentUniversity of Medical Center, Nashville, Tennessee, USA have published the research work: Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy, in the Journal: (JOURNAL)
• How: Concurrent with these discoveries has been a renewed realization that standard cell culture media were not designed to mimic the nutrient environment found in_vivo but were designed to provide excess amounts of the minimal nutrients required to sustain cancer cell growth in_vitro .
• Future: Studies will be required to determine whether uric acid directly interacts . . .
  

   

  

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