Dual antigen t cell engagers targeting ca9 as an effective immunotherapeutic modality for targeting ca9 in solid tumors

HIGHLIGHTS

  • who: Nazanin Tatari from the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada, Centre for Discovery have published the research: Dual Antigen T Cell Engagers Targeting CA9 as an Effective Immunotherapeutic Modality for Targeting CA9 in Solid Tumors, in the Journal: (JOURNAL)
  • what: The authors demonstrate that the DATE is exquisitely specific for CA9 expressing patient-derived models of ccRCC and GBM. Upon confirming the antigen specificity of the CA9 DATE for both T_cells and tumor cells, the authors aimed to assess the efficacy of the CA9 DATE by further investigating its . . .

     

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