HIGHLIGHTS
- who: HDAC inhibitor and colleagues from the University of Padua, Italy have published the Article: Dual Blockade of Misfolded Alpha-Sarcoglycan Degradation by Bortezomib and Givinostat Combination, in the Journal: (JOURNAL)
- what: While in this classification, givinostat was ranked in the top 10 compounds , the review of various factors of the top compounds such as their clinical approval stage, their indications, and their targets, highlighted givinostat as one of the most promising orphan_drugs to be investigated for its effect on u03b1-SG. Drugs identified, the authors report the particular effect of HDACi with eight HDACi . . .
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