Dual effect of lithium on nfat5 activity in kidney cells

HIGHLIGHTS

  • who: Christoph Küper from the Department of, University of Munich, Munich, Germany, Medical Clinic V, University Hospital Mannheim have published the research: Dual effect of lithium on NFAT5 activity in kidney cells, in the Journal: (JOURNAL)
  • what: The aim of this study was to evaluate the effects of lithium on the activity of NFAT5.

SUMMARY

    The most common adverse effect is nephrogenic diabetes insipidus (NDI), due to a decreased expression of the aquaporin-2 (AQP-2) water channel and incorrect trafficking of AQP-2 to the luminal membrane in collecting . . .

     

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