Dual hdac-brd4 inhibitors endowed with antitumor and antihyperalgesic activity

HIGHLIGHTS

  • who: Soumia Maach from the Department of Neurosciences, Psychology, Drug Research and Child Health (NeuroFarBa), University of Florence, Florence, Italy have published the research work: Dual HDAC-BRD4 inhibitors endowed with antitumor and antihyperalgesic activity, in the Journal: (JOURNAL) of 22/09/2010
  • what: The authors report the design synthesis and activity of new obtained by adding a methyltriazole moiety to some HDAC carrying a benzodiazepine core which were previously developed by us. While this work was in progress, compounds with structure similar to 6, deriving from hybridization of SAHA and JQ1, were reported in . . .

     

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