HIGHLIGHTS
- who: EZH and colleagues from the India Ben-Gurion University of the Negev have published the Article: Dual inhibition of EZH2 and G9A/ GLP histone methyltransferases by HKMTI-1-005 promotes differentiation of acute myeloid leukemia cells, in the Journal: (JOURNAL)
- what: The aim of this study was to assess whether EZH2 played a role in myeloid differentiation of human non-APL AML, which had not been previously evaluated, and, if so, whether small_molecule inhibitors of EZH2 could be effective in combination with ATRA. By taking different approaches to functionally impair EZH2 activity the authors . . .
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