Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations

HIGHLIGHTS

• who: Danielle P. M. LeBlanc from the (UNIVERSITY) have published the paper: Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations, in the Journal: (JOURNAL)
• what: The authors demonstrate that DS is a promising approach to study in vivo mutagenesis and yields critical insight into the features governing and variability across the genome. The authors demonstrate that analyses restricted to single trinucleotides can correctly classify BaP-exposed samples.
• how: In this analysis only the controls and the BaP high dose samples were used.
• future . . .
  

   

  

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