HIGHLIGHTS
SUMMARY
To date, few studies have examined the genome organization of endothelial cells (Niskanen et_al, 2018; Rao et_al, 2014), and none have made use of a model for endothelial cell differentiation in which all samples are clonal, having been differentiated from the same source. To fill this gap, the authors performed a modified version of a previously developed protocol to induce endocardial-like endothelial differentiation from human pluripotent stem_cells (hPSCs; Palpant et_al, 2015, 2017) and, taking advantage of in situ DNase Hi-C (Ramani et_al, 2016), a form of high-throughput chromosome conformation capture with . . .
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