Dynamic enlargement and mobilization of lipid droplets in pluripotent cells coordinate morphogenesis during mouse peri-implantation development

HIGHLIGHTS

  • who: King Hang Tommy Mau from the Institute Vu00e9tu00e9rinaire d`Alfort, BREED, Maison-Alfort, FranceUniversity of have published the paper: Dynamic enlargement and mobilization of lipid droplets in pluripotent cells coordinate morphogenesis during mouse peri-implantation development, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: Mechanistically, the authors show that pre-implantation blastocysts and pluripotent ESCs share the ability to transiently fuse and enlarge LDs under the tight control of the LD-surface protein CIDEA.
  • how: All downstream analysis was carried out in R using Bioconductor packages.

SUMMARY

    Interestingly . . .

     

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