Dynamic interactions of post cleaved ns2b cofactor and ns3 protease identified by integrative structural approaches

HIGHLIGHTS

  • who: Jun-Ping Quek and colleagues from the Lee Kong Chian School of Medicine, Technological University, EMB, have published the paper: Dynamic Interactions of Post Cleaved NS2B Cofactor and NS3 Protease Identified by Integrative Structural Approaches, in the Journal: Viruses 2022, 1436 of /2022/
  • what: Combining LC-MS analysis and X-ray crystallography, the authors provide structural basis of NS2B C-terminus occupying NS2B-NS3 active_site. The analysis showed that no cleavage of NS2B from 1 h and 18 h . When the authors compare the surface charge density of eNS2B47 NS3Pro with that the published . . .

     

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