HIGHLIGHTS
- who: Robert J. Lake et al. from the Division of Molecular Medicine, Department of Internal Medicine, University of New Mexico Comprehensive have published the research: Dynamic Interplay between Cockayne Syndrome Protein B and Poly(ADP-Ribose) Polymerase 1 during Oxidative DNA Damage Repair, in the Journal: Biomedicines 2022, 10, 361. of /2022/
- what: By extending the analysis , the authors show that the crosstalk between CSB and PARP1 occurs at a genome-wide level. By measuring PARylation levels on oxidatively damaged chromatin, the authors demonstrate that CSB sustains chromatin PARylation initiated by PARP1 . In the Lee . . .
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