Dynamic multimerization of dab2-myosin vi complexes regulates cargo processivity while minimizing cortical actin reorganization

HIGHLIGHTS

• who: Ashim Rai from the (UNIVERSITY) have published the paper: Dynamic multimerization of Dab2-Myosin VI complexes regulates cargo processivity while minimizing cortical actin reorganization, in the Journal: (JOURNAL) of January/16,/2020
• what: The authors demonstrate that dynamic multimerization of myosin VI-Dab2 complexes facilitates cargo processivity without significant reorganization of cortical actin networks. Taken together, the study demonstrates the importance of dynamic motor-cargo association in enabling cargo transportation without disrupting cytoskeletal organization. The functional implications of the Dab2 MIR:myosin VI CBD complex on myosin VI motility have not yet been elucidated . . .
  

   

  

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