Dynamic o-glcnacylation coordinates ferritinophagy and mitophagy to activate ferroptosis

HIGHLIGHTS

• who: Fan Yu from the (UNIVERSITY) have published the Article: Dynamic O-GlcNAcylation coordinates ferritinophagy and mitophagy to activate ferroptosis, in the Journal: (JOURNAL)
• what: The authors report that protein the primary nutrient sensor of glucose flux orchestrates both ferritinophagy and mitophagy for ferroptosis. Error bars indicate SD. fragmentation is the prerequisite to mitophagy41-44, the authors reason that these fragmented mitochondria were prone to mitophagy. The authors show that the protein O-GlcNAcylation regulates ferritinophagy and mitochondria behaviors to dictate ferroptosis.
• how: This result was in accordance with the assumption that some . . .
  

   

  

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