Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression

HIGHLIGHTS

• who: Fan Zhang and collaborators from the Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Oak St, University of British Columbia, Vancouver, BC V T , Canada have published the article: Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression, in the Journal: (JOURNAL)
• what: The authors demonstrate that foci formation correlates with AR transcriptional activity as this activity can be modulated by changing cellular foci content chemically or by silencing MED1. Using a variety of molecular biology and biophysical approaches the authors demonstrate that full-length . . .
  

   

  

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