Dynamic phenomena and complexation effects in the -lithiation and asymmetric functionalization of azetidines

HIGHLIGHTS

• who: Pantaleo Musci and collaborators from the Department of Pharmacy-Drug, University of Bari "AMoro", Via Orabona, Bari, Italy have published the research work: Dynamic Phenomena and Complexation Effects in the -Lithiation and Asymmetric Functionalization of Azetidines, in the Journal: Molecules 2022, 27, x FOR PEER REVIEW of /2022/
• what: In this work it is demonstrated that enantiomerically enriched N-alkyl 2-oxazolinylazetidines undergo exclusive and that the resulting lithiated intermediate is chemically stable but configurationally labile under the given experimental conditions that afford enantioenriched N-alkyl-2 2-disubstituted azetidines. The authors report herein . . .
  

   

  

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