Dynamic rewiring of biological activity across genotype and lineage revealed by context-dependent functional interactions

HIGHLIGHTS

  • who: Eiru Kim from the Department of Cancer, The University of Texas MD Anderson USA have published the research work: Dynamic rewiring of biological activity across genotype and lineage revealed by context-dependent functional interactions, in the Journal: (JOURNAL)
  • what: The authors provide an online resource to explore these context-dependent interactions at diffnet.hart-lab.org. Rewiring detected by the approach showed concordance with biological knowledge and discovered new putative context-dependent functional interactions, demonstrating its potential for functional genomics and cancer targeting. The authors provide a web-based interface for exploring the network . . .

     

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