Dynamic single-cell rna-seq analysis reveals distinct tumor program associated with microenvironmental remodeling and drug sensitivity in multiple myeloma

HIGHLIGHTS

  • who: Mengping Chen from the Department of Hematology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China have published the research work: Dynamic single-cell RNA-seq analysis reveals distinct tumor program associated with microenvironmental remodeling and drug sensitivity in multiple myeloma, in the Journal: (JOURNAL)
  • what: By scoring NDMM samples in CoMMpass cohort, the authors found limited impacts of stress program in patient prognosis (Additional file 1: Fig S9A, B), therefore the authors focused on the immune reactive signature. By scoring tumor cells from this study, the authors found that immune . . .

     

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