Dynamical modeling of mir-34a, mir-449a, and mir-16 reveals numerous ddr signaling pathways regulating senescence, autophagy, and apoptosis in hela cells

HIGHLIGHTS

  • who: Shantanu Gupta from the InstitutUniversidade, Bhubaneswar, India have published the research: Dynamical modeling of miR-34a, miR-449a, and miR-16 reveals numerous DDR signaling pathways regulating senescence, autophagy, and apoptosis in HeLa cells, in the Journal: Scientific Reports Scientific Reports

SUMMARY

    | 1 Vol.:(0123456789) research shows that these miRNAs may potentially play a role in autophagy signaling. Huang et_al7 demonstrated the involvement of miR-16 in the activation of autophagy by targeting mTOR-2 within this framework. Similarly, Rathod et_al8 established that miR-34a targets mTOR-2 directly. When glioma and . . .

     

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