Dynamical modeling of the h3k27 epigenetic landscape in mouse embryonic stem cells

HIGHLIGHTS

  • who: Kapil Newar and colleagues from the Claude Bernard Lyon, Lyon, Francesupported by the University Grenoble-Alpes via the have published the Article: Dynamical modeling of the H3K27 epigenetic landscape in mouse embryonic stem cells, in the Journal: (JOURNAL)
  • what: Within the biological context of mouse embryonic stem cells the model showed quantitative agreement with experimental profiles of H3K27 acetylation and methylation around Polycomb-target genes in wild-type and mutants. The authors aim to provide a modeling framework able to quantitatively describe the genomic profiles of epigenetic marks in the context of the Polycomb . . .

     

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