HIGHLIGHTS
SUMMARY
Healthy volunteers or patients, used sparse samples and did not fully reveal the dynamics of ERFE (Kautz et_al, 2015; Honda et_al, 2016; Bondu et_al, 2019; Hara et_al, 2019; Ramirez Cuevas et_al, 2020; Pirotte et_al, 2021). Erythroferrone (ERFE) is a newly identified hormone that plays a vital role in iron homeostasis and erythropoiesis (Kautz et_al, 2014a; Srole and Ganz, 2021). As a master regulator connecting erythropoiesis and iron metabolism, ERFE evokes much research interests in many research fields such as thalassemia, myelodysplastic syndromes, chronic kidney disease, anti-doping, hematopoietic stem_cell transplant (Kautz et_al, 2015; Bondu . . .
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