HIGHLIGHTS
- who: Eun-Young Kim from the Department of Biomedical Sciences, Asan Medical Center, University Republic of have published the article: Dysfunction in parkin aggravates inflammatory bone erosion by reinforcing osteoclast activity, in the Journal: (JOURNAL)
- what: The authors report that Parkin-deficient mice display a reduced bone mass accompanied by increased OC activity via the regulation of u03b1-tubulin acetylation and are susceptible to bone loss under an inflammatory condition.
- how: The authors showed from the current analysis that Parkin-deficient mice exhibit a more severe phenotype in terms of inflammation-mediated bone . . .
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