Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury

HIGHLIGHTS

• who: Wulf Tonnus from the Assessment of stability in human plasmaTo determine the stability of the Nec1f in human plasma (plasma stability assay was carried by ENAMINE Ltd [, ]. Ukraine), Nec-1f and reference compounds were analyzed and compared at five time points over , min using HPLC-MS/MS. Plasma stability is defined as the percentage of parent compound remaining in plasma over the time. Here, incubations were carried out in , aliquots of , µl each (one for each time point), in duplicates. Nec-1f and respective controls (, µM, final DMSO concentration, %) were incubated at , °C with shaking at . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.