Dysregulated ceramide metabolism in mouse progressive dermatitis resulting from constitutive activation of jak1

HIGHLIGHTS

• who: Yudai Iino from the DivisionKeio University, Yokohama, Japan have published the Article: Dysregulated ceramide metabolism in mouse progressive dermatitis resulting from constitutive activation of Jak1, in the Journal: (JOURNAL)
• what: The authors performed untargeted and targeted lipidomic analyses to determine the global lipid profiling in a progressive AD-like dermatitis of Spade mice that can spontaneously develop pruritic dermatitis by the mutation of the gene encoding Janus kinase 1 (Jak1), causing constitutive activation of Jak1 signaling . Since ceramide metabolism was altered in Spade mice before AD onset, the authors focused on its metabolism.
 



If you want to have access to all the content you need to log in!

Thanks :)

Username or Email

Password

Remember me

Lost your password?

If you don't have an account, you can create one here.