Dysregulation of bile acids increases the risk for preterm birth in pregnant women

HIGHLIGHTS

• who: Sangmin You from the College University of Rhode Island, Greenhouse Road, Kingston, RI, USA have published the research: Dysregulation of bile acids increases the risk for preterm birth in pregnant women, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: In this study, a hospital-based cohort study with pregnant women is conducted. The authors used CCl4 as a challenging agent to induce liver injury and bile acid dysregulation and investigate the effects on PTB in pregnant mice. The authors demonstrated that restoring the bile acid homeostasis by FXR activation significantly reduced CCl4-induced PTB . . .
  

   

  

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