Dysregulation of cellular vrk1, baf, and innate immune signaling by the vaccinia virus b12 pseudokinase

HIGHLIGHTS

• who: Alexandria C. Linville et al. from the Nebraska Center for Virology, University of Nebraska, Lincoln, Nebraska, USA have published the article: Dysregulation of Cellular VRK1, BAF, and Innate Immune Signaling by the Vaccinia Virus B12 Pseudokinase, in the Journal: (JOURNAL) of 11/05/2022
• what: The authors further characterize functional linkages between B12 and cellular pathways involving VRK1, BAF, and innate immune signaling. Next, the authors demonstrate that B12 also impacts the localization of BAF, causing BAF to repartition predominantly to the nucleus in a manner correlating with reduced BAF phosphorylation. To begin the . . .
  

   

  

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